Novel Coarse-Graining Approaches for Large Scale Protein Modeling
نویسندگان
چکیده
منابع مشابه
Markov Methods for Hierarchical Coarse-Graining of Large Protein Dynamics
Elastic network models (ENMs) and, in particular, the Gaussian Network Model (GNM) have been widely used in recent years to gain insights into the machinery of proteins. The extension of ENMs to supramolecular assemblies presents computational challenges, because of the difficulty in retaining atomic details in mode decomposition of large protein dynamics. Here, we present a novel approach to a...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2018
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2017.11.3141